4+ hour, 44+ min ago   (436+ words) A late-life experiment reveals how a widely used metabolic drug reshapes age-related physiology and molecular pathways, with effects that both resemble and differ from calorie restriction. Study: Late-life semaglutide treatment slows ageing and extends lifespan in female mice. Image Credit:…...

2+ day, 9+ hour ago   (166+ words) Senescent cells - cells that have stopped dividing but remain metabolically active - can accumulate with age and contribute to chronic inflammation and tissue dysfunction. A new Mini Review in Geromedicine examines a protein interaction that may help some of these cells…...

1+ week, 2+ day ago   (374+ words) A recent study from the University of Jyväskylä, Finland, shows that physical activity declines substantially with age, even among older adults who are in good physical condition. Over a four-year follow-up period, physical activity energy expenditure decreased by an average…...

2+ week, 1+ hour ago   (513+ words) Now, a new study not only redefines our understanding of senescence but also illustrates how to prevent its harmful effects. The findings, published in Life Science Alliance, reveal that senescence unfolds in stages-not all at once as previously thought-and that…...

2+ week, 2+ day ago   (289+ words) News-Medical Researchers develop new tool to estimate a cell's biological age Researchers at Karolinska Institutet and Stockholm University have developed a new tool that estimates a cell's biological age by analyzing its gene activity. In the journal Advanced Science, they…...

2+ week, 3+ day ago   (347+ words) A research team led by Professor Keisuke Goda of the SiRIUS Institute of Medical Research and Graduate School of Medicine at Tohoku University, together with the Department of Chemistry at the University of Tokyo, has been named a Milestone 2 Awardee…...

2+ week, 3+ day ago   (369+ words) In humans and many other animals, a mother's age can affect the physical and behavioral characteristics of the next generation. Scientists call these changes maternal age effects, and while they are widespread across the animal kingdom, researchers still don't fully…...

3+ week, 2+ day ago   (369+ words) Simple tests of balance, strength, mobility, and endurance may offer clinicians an objective window into physiological reserve and help identify older adults at greater risk of death. Study: Physical Fitness and All-Cause Mortality in Older Adults. Image Credit: Dusan Petkovic…...

1+ mon, 1+ week ago   (361+ words) A major global analysis shows that survival gains are outpacing healthy aging, shifting the public health challenge from living longer to living better. GBD Level 2 cause decomposition of the morbidity gap globally and by GBD super-region, 1990 and 2023. Study: GBD Level…...

1+ mon, 1+ week ago   (426+ words) Skeletal muscle is one of the first tissues to decline with age. This decline can lead to weakness, scarring, fat accumulation inside muscle, and the loss of fast-twitch muscle fibers that are important for quick and powerful movements. A research…...