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Scientists find how “zombie” cells fuel inflammation as we age
5+ hour, 29+ min ago (594+ words) Scientists discovered that aging cells can use malfunctioning mitochondria to unlock inflammatory genes and keep the immune system stuck in a prolonged state of alert. Blocking one part of this process reduced inflammation and improved healthy aging in mice, suggesting…...
Scientists discover a hidden switch that shuts down inflammation
1+ day, 7+ hour ago (659+ words) Scientists have uncovered a natural braking system that helps the immune system switch off inflammation and prevent harmful immune cells from building up. Boosting this pathway in people reduced inflammation-related immune changes and sped up pain relief, pointing toward potential…...
UCLA scientists turn cord blood into powerful cancer-fighting T cells
3+ day, 8+ hour ago (1233+ words) UCLA researchers developed ready-made cancer-fighting T cells from cord blood stem cells that can attack solid tumors through two separate detection systems. In mice, a single dose controlled cancer and extended survival while avoiding a dangerous complication associated with donor-derived…...
Scientists find a new weakness in treatment-resistant prostate cancer
5+ day, 22+ hour ago (488+ words) Researchers have found a potential way to attack prostate cancers that evade treatment by changing their cellular identity. Combining two types of drugs reversed many of these changes and sharply slowed tumor growth in preclinical experiments, offering a possible new…...
Early statin use linked to 15% lower dementia risk
6+ day, 1+ hour ago (254+ words) Starting statins soon after a type 2 diabetes diagnosis may do more than protect the heart. In a nationwide Danish study of more than 132,000 people, those who began statin treatment within a year of diagnosis had a 15% lower relative risk of…...
Scientists discover a hidden immune signal that helps spinal cords regrow
6+ day, 8+ hour ago (199+ words) A surprising immune system signal may help explain why zebrafish can regenerate damaged spinal cords so effectively. Researchers found that certain neutrophils release Il-4, which calms harmful inflammation and allows injured nerve fibers to grow again. Without these cells, healing stalled,…...
Your gut microbiome may be more contagious than scientists thought
1+ week, 2+ hour ago (699+ words) The human gut is home to trillions of microorganisms (the microbiome), a vast community that helps shape digestion, immune function and metabolism. Now, researchers led by the University of Vienna have found that many gut bacterial species are more complex…...
MIT scientists develop injectable “mini livers” that work inside the body
1+ week, 5+ hour ago (646+ words) MIT engineers have developed injectable “mini livers” designed to help support people whose failing livers can no longer perform essential jobs. Instead of replacing the damaged organ, the approach injects liver cells together with tiny hydrogel spheres and supportive cells,…...
Scientists find breast cancer cells hiding behind protective “shields”
1+ week, 12+ hour ago (648+ words) Researchers have mapped breast tumors in striking detail and uncovered hidden pockets of dormant cancer cells that may help explain why cancer can return after treatment. Unlike rapidly dividing cells, these quiet cells can essentially hibernate, allowing them to evade…...
Clarifying the cellular mechanisms underlying periodontitis with an improved animal model
1+ week, 3+ day ago (91+ words) In a study recently published in Nature Communications on March 28, 2024, researchers from Tokyo Medical and Dental University (TMDU) found a way to achieve this by improving upon a widely used animal model to study periodontitis. Materials provided by Tokyo Medical…...